N-Deacetyl-N-methylcolchicine (Colcemid) is related to colchicine but it is less toxic. Colcemid depolymerizes microtubules and limits their formation. Appropriate dilutions inactivate the spindle fiber formation, thus arresting cells in metaphase and allowing cell harvest and karyotyping to be performed.
Applications:
No.
Volume:
10 mlAdd to order
Product specifications
Clear liquid
477-30-5
Store at +2 to +8°C upon arrival.
Once opened store at +2 to +8°C and use within 4-6 weeks.
Ambient
Recommended final concentration: 0.1 µg/ml
| Component | concentration mg/l |
| Demecolcine (Colcemid) | 10.00 |
| CaCl₂ 2H₂O | 130.00 |
| Cl₂Mg 6H₂O | 100.00 |
| KCl | 200.00 |
| KH2PO4 | 200.00 |
| NaCl | 8000.00 |
| Na2HPO4 | 1150.00 |
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N-Deacetyl-N-methylcolchicine (Colcemid) is related to colchicine but it is less toxic. Colcemid depolymerizes microtubules and limits their formation. Appropriate dilutions inactivate the spindle fiber formation, thus arresting cells in metaphase and allowing cell harvest and karyotyping to be performed.
Applications:
General information in pdf