Helios Oligo dT affinity resin is a new type of high rigid polymer resin, which is mainly used for the separation and purification of mRNA. Helios Oligo dT is based on polystyrene, and the surface is covered with a large number of hydroxyl groups. The functionalized poly dT group can efficiently capture mRNA by base pairing with the poly-A tail of mRNA and improve production efficiency. Resin has high selectivity and extremely low non-specific adsorption.