Persefose 4FF is a highly cross-linked (cross-linking ratio of 4%) agarose-based gel filtration chromatography resin, which separates different molecules by using their molecular weight and conformation differences. This chromatographic resin can be used successfully for the separation and purification of various biological molecules such as recombinant proteins, antibodies, nucleic acids, viruses and virus-like particles, and polysaccharides.

Persefose 4FF has excellent scale-up capabilities:

(1) It has a highly cross-linked agarose matrix with excellent rigidity. On the one hand, the restriction on column bed height is reduced; on the other hand, high process flow rate can be achieved under low back pressure, improving process efficiency.

(2) An improved ball-making process achieves a smaller diffusion effect and provides better resolution.